top of page

Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in

  • nicksanzo
  • May 3, 2018
  • 1 min read

SETX ALS4 mice thus recapitulated ALS disease phenotypes in association with TDP-43 mislocalization and provided insight into the basis for TDP-43 histopathology, linking SETX dysfunction to common pathways of ALS motor neuron degeneration.

You can read the full paper here: https://doi.org/10.1007/s00401-018-1852-9

 
 
 

Comentarios


Featured Posts
Recent Posts
Search By Tags
Archive
Follow Us
  • Facebook Basic Square
  • Twitter Basic Square
  • Google+ Basic Square
bottom of page